Gene

Bnip3l

Species
Rattus norvegicus
Symbol
Bnip3l
Name
BCL2 interacting protein 3 like
Synonyms
  • BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
  • BCL2/adenovirus E1B 19 kDa-interacting protein 3-like
Biotype
protein coding gene
Automated Description
Predicted to enable lamin binding activity and protein homodimerization activity. Involved in negative regulation of mitochondrial membrane potential; positive regulation of apoptotic process; and positive regulation of mitochondrial membrane permeability. Predicted to be located in endoplasmic reticulum; mitochondrial outer membrane; and nucleus. Biomarker of gestational diabetes; metabolic dysfunction-associated steatohepatitis; middle cerebral artery infarction; and pancreatitis. Orthologous to human BNIP3L (BCL2 interacting protein 3 like).
RGD Description
Predicted to enable lamin binding activity and protein homodimerization activity. Involved in negative regulation of mitochondrial membrane potential; positive regulation of apoptotic process; and positive regulation of mitochondrial membrane permeability. Predicted to be located in mitochondrion and nuclear speck. Predicted to be active in endoplasmic reticulum; mitochondrial outer membrane; and nuclear envelope. Biomarker of gestational diabetes; middle cerebral artery infarction; and pancreatitis. Orthologous to human BNIP3L (BCL2 interacting protein 3 like); PARTICIPATES IN intrinsic apoptotic pathway; mitochondrial autophagy pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR15186
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Alleles and Variants

Genome location
Assembly version
mRatBN7.2
Viewer Help
41.176M41.178M41.180M41.182M41.184M41.186M41.188M41.190M41.192M41.194M41.196M
Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
NC_051350.1:g.41184681G>Avariant
SNP
  • intron variant
NC_051350.1:g.41184774C>Gvariant
SNP
  • intron variant
NC_051350.1:g.41184444T>Cvariant
SNP
  • intron variant
NC_051350.1:g.41189087T>Cvariant
SNP
  • intron variant
NC_051350.1:g.41181989T>Cvariant
SNP
  • intron variant
NC_051350.1:g.41179131T>Avariant
SNP
  • intron variant
NC_051350.1:g.41179015A>Gvariant
SNP
  • intron variant
NC_051350.1:g.41184113A>Gvariant
SNP
  • intron variant
NC_051350.1:g.41193969C>Tvariant
SNP
  • intron variant
NC_051350.1:g.41184116A>Gvariant
SNP
  • intron variant
Showing 1 - 10 of 22 rows
per page

Transgenic Alleles

No data available

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
41.176M41.178M41.180M41.182M41.184M41.186M41.188M41.190M41.192M41.194M41.196M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions

No data available