Gene

Atp5f1b

Species
Rattus norvegicus
Symbol
Atp5f1b
Name
ATP synthase F1 subunit beta
Synonyms
  • ATP synthase subunit beta, mitochondrial
  • ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit
Biotype
protein coding gene
Automated Description
Enables adenyl ribonucleotide binding activity; calcium ion binding activity; and lipoprotein particle receptor activity. Contributes to ATP hydrolysis activity. Involved in several processes, including cellular response to peptide; cold acclimation; and response to 3,3',5-triiodo-L-thyronine. Located in cell surface; membrane raft; and mitochondrial inner membrane. Part of proton-transporting ATP synthase complex, catalytic core F(1). Used to study obesity. Biomarker of cardiomyopathy; polycystic ovary syndrome; transient cerebral ischemia; and type 2 diabetes mellitus. Orthologous to human ATP5F1B (ATP synthase F1 subunit beta).
RGD Description
Enables adenyl ribonucleotide binding activity; calcium ion binding activity; and lipoprotein particle receptor activity. Contributes to ATP hydrolysis activity. Involved in several processes, including cellular response to peptide; cold acclimation; and response to 3,3',5-triiodo-L-thyronine. Located in cell surface; membrane raft; and mitochondrial inner membrane. Part of proton-transporting ATP synthase complex, catalytic core F(1). Used to study obesity. Biomarker of cardiomyopathy; polycystic ovary syndrome; transient cerebral ischemia; and type 2 diabetes mellitus. Orthologous to human ATP5F1B (ATP synthase F1 subunit beta); PARTICIPATES IN electron transport chain pathway; Alzheimer's disease pathway; Huntington's disease pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1,3-dinitrobenzene; 17alpha-ethynylestradiol.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR15184
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
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    Disease Associations

    Cases where the expected disease association was NOT found
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      Alleles and Variants

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        Transgenic Alleles

        Species
        (carrying the transgene)
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          Models

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            Sequence Feature Viewer

            Genome location
            Assembly version
            mRatBN7.2
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            520k525k530k535k540k545k550k555k560k565k

            Sequence Details

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            Expression

            Primary Sources
            None
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            Atp5f1b molecule type
            Interactor gene
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              Genetic Interactions

              Atp5f1b role
              Atp5f1b genetic perturbation
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