Version: 8.0.0
Date: Tue Jan 28 2025
Gng12
Rattus norvegicusRGD:621516
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Gng12

Species
Rattus norvegicus
Symbol
Gng12
Name
G protein subunit gamma 12
Synonyms
  • guanine nucleotide binding protein (G protein), gamma 12
  • guanine nucleotide binding protein 12
Biotype
protein coding gene
Automated Description
Enables phosphate ion binding activity. Involved in cerebral cortex development and response to lipopolysaccharide. Located in actin filament. Orthologous to human GNG12 (G protein subunit gamma 12).
RGD Description
Enables phosphate ion binding activity. Involved in cerebral cortex development and response to lipopolysaccharide. Located in actin filament. Orthologous to human GNG12 (G protein subunit gamma 12); PARTICIPATES IN adenosine signaling pathway; dopamine signaling pathway via D1 family of receptors; follicle-stimulating hormone signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,2,2-tetramine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13809
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    No data available

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
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      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
      Has Disease Annotations
      Has Phenotype Annotations
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        Models

        Model name
        Experimental condition
        Associated Human Diseases
        Associated Phenotypes
        Modifier
        Source
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          Sequence Feature Viewer

          Genome location
          Assembly version
          mRatBN7.2
          Viewer Help
          Data currently unavailable; sequence viewer under construction

          Sequence Details

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          Expression

          Primary Sources
          None
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          Gng12 molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection methods
          Source
          Reference
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            Genetic Interactions

            Gng12 role
            Gng12 genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
            Source
            Reference
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