Version: 8.0.0
Date: Tue Jan 28 2025
Kif3a
Rattus norvegicusRGD:621536
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Kif3a

Species
Rattus norvegicus
Symbol
Kif3a
Name
kinesin family member 3a
Synonyms
  • kinesin-like protein KIF3A
Biotype
protein coding gene
Automated Description
Enables kinesin binding activity. Involved in positive regulation of establishment or maintenance of cell polarity regulating cell shape; positive regulation of transport; and response to silicon dioxide. Located in neuronal cell body; plasma membrane bounded cell projection cytoplasm; and ribbon synapse. Biomarker of silicosis. Orthologous to human KIF3A (kinesin family member 3A).
RGD Description
Enables kinesin binding activity. Involved in positive regulation of establishment or maintenance of cell polarity regulating cell shape; positive regulation of transport; and response to silicon dioxide. Located in neuronal cell body; plasma membrane bounded cell projection cytoplasm; and ribbon synapse. Biomarker of silicosis. Orthologous to human KIF3A (kinesin family member 3A); PARTICIPATES IN Hedgehog signaling pathway; insulin responsive facilitative sugar transporter mediated glucose transport pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR47968
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    No data available

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
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      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
      Has Disease Annotations
      Has Phenotype Annotations
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        Models

        Model name
        Experimental condition
        Associated Human Diseases
        Associated Phenotypes
        Modifier
        Source
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          Sequence Feature Viewer

          Genome location
          Assembly version
          mRatBN7.2
          Viewer Help
          Data currently unavailable; sequence viewer under construction

          Sequence Details

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          Expression

          Primary Sources
          None
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          Kif3a molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection methods
          Source
          Reference
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            Genetic Interactions

            Kif3a role
            Kif3a genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
            Source
            Reference
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