gamma-aminobutyric acid type A receptor subunit alpha 4
Synonyms
GABA-A receptor alpha-4 subunit
GABA(A) receptor subunit alpha-4
Biotype
protein coding gene
Automated Description
Enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in several processes, including GABAergic synaptic transmission; chloride transmembrane transport; and inhibitory synapse assembly. Predicted to act upstream of or within central nervous system development. Is active in GABA-ergic synapse and postsynaptic specialization membrane. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human GABRA4 (gamma-aminobutyric acid type A receptor subunit alpha4).
RGD Description
Enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in several processes, including GABAergic synaptic transmission; chloride transmembrane transport; and inhibitory synapse assembly. Predicted to act upstream of or within central nervous system development. Is active in GABA-ergic synapse and postsynaptic specialization membrane. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human GABRA4 (gamma-aminobutyric acid type A receptor subunit alpha4); INTERACTS WITH (+)-pilocarpine; 17beta-estradiol; 17beta-estradiol 3-benzoate.