Gene

Grin3a

Species
Rattus norvegicus
Symbol
Grin3a
Name
glutamate ionotropic receptor NMDA type subunit 3A
Synonyms
  • chi-1
  • GluN3A
Biotype
protein coding gene
Automated Description
Enables carboxylic acid binding activity; glutamate-gated receptor activity; and protein phosphatase 2A binding activity. Contributes to NMDA glutamate receptor activity. Involved in several processes, including ionotropic glutamate receptor signaling pathway; monoatomic cation transport; and negative regulation of dendritic spine development. Located in cytoplasm and postsynaptic membrane. Part of NMDA selective glutamate receptor complex. Is active in glutamatergic synapse and postsynaptic density membrane. Orthologous to human GRIN3A (glutamate ionotropic receptor NMDA type subunit 3A).
RGD Description
Enables glutamate-gated receptor activity; glycine binding activity; and protein phosphatase 2A binding activity. Contributes to NMDA glutamate receptor activity. Involved in several processes, including calcium ion transport; ionotropic glutamate receptor signaling pathway; and negative regulation of dendritic spine development. Located in cytoplasm and postsynaptic membrane. Part of NMDA selective glutamate receptor complex. Is active in glutamatergic synapse and postsynaptic density membrane. Orthologous to human GRIN3A (glutamate ionotropic receptor NMDA type subunit 3A); PARTICIPATES IN excitatory synaptic transmission pathway; alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR18966
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
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    Disease Associations

    Cases where the expected disease association was NOT found
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    Alleles and Variants

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      Transgenic Alleles

      Species
      (carrying the transgene)
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        Models

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          Sequence Feature Viewer

          Genome location
          Assembly version
          mRatBN7.2
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          Data currently unavailable; sequence viewer under construction

          Sequence Details

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          Expression

          Primary Sources
          None
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          Grin3a molecule type
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            Genetic Interactions

            Grin3a role
            Grin3a genetic perturbation
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