Gene

Oas1a

Species
Rattus norvegicus
Symbol
Oas1a
Name
2'-5' oligoadenylate synthetase 1A
Synonyms
  • (2-5')oligo(A) synthase 1
  • (2-5')oligo(A) synthase 1A
Biotype
protein coding gene
Automated Description
Enables 2'-5'-oligoadenylate synthetase activity. Predicted to be involved in several processes, including cellular response to cytokine stimulus; regulation of cytokine production; and regulation of innate immune response. Located in nucleus. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human OAS1 (2'-5'-oligoadenylate synthetase 1).
RGD Description
Enables 2'-5'-oligoadenylate synthetase activity. Predicted to be involved in several processes, including cellular response to cytokine stimulus; regulation of cytokine production; and regulation of innate immune response. Located in nucleus. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human OAS1 (2'-5'-oligoadenylate synthetase 1); PARTICIPATES IN hepatitis C pathway; influenza A pathway; measles pathway; INTERACTS WITH 3,3',4,4',5-pentachlorobiphenyl; Actein; bisphenol A.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11258
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
35.670M35.671M35.672M35.673M35.674M35.675M35.676M35.677M35.678M35.679M35.680M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions