Version: 8.0.0Date: Tue Jan 28 2025
Gene
Rheb
- Species
- Rattus norvegicus
- Symbol
- Rheb
- Name
- Ras homolog, mTORC1 binding
- Synonyms
- GTP-binding protein Rheb
- Ras homolog enriched in brain
- Biotype
- protein coding gene
- Automated Description
- Enables GDP binding activity; GTP binding activity; and GTPase activity. Involved in regulation of postsynapse organization and small GTPase-mediated signal transduction. Located in dendrite and neuronal cell body. Is active in glutamatergic synapse. Orthologous to human RHEB (Ras homolog, mTORC1 binding).
- RGD Description
- Enables GDP binding activity; GTP binding activity; and GTPase activity. Involved in regulation of postsynapse organization and small GTPase-mediated signal transduction. Located in dendrite and neuronal cell body. Is active in glutamatergic synapse. Orthologous to human RHEB (Ras homolog, mTORC1 binding); PARTICIPATES IN mTOR signaling pathway; insulin signaling pathway; Rheb mediated signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
- Cross References
- Additional Information
- Literature
Orthology
- Gene tree
- PANTHER:PTHR24070
Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse
Disease Associations
Cases where the expected disease association was NOT found
Cell color indicative of annotation volume
Sequence Feature Viewer
- Genome location
- Chr4:10278970...10320160 + (41.19 kb)
- Assembly version
- mRatBN7.2
- Viewer Help
Data currently unavailable; sequence viewer under construction