Gene

Mt-co2

Species
Rattus norvegicus
Symbol
Mt-co2
Name
mitochondrially encoded cytochrome c oxidase II
Synonyms
  • Co2
  • COII
Biotype
protein coding gene
Automated Description
Predicted to enable copper ion binding activity. Predicted to contribute to cytochrome-c oxidase activity. Involved in lactation and response to hypoxia. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex IV. Biomarker of acute myocardial infarction; colorectal carcinoma; and type 2 diabetes mellitus. Orthologous to several human genes including MT-CO2 (mitochondrially encoded cytochrome c oxidase II).
RGD Description
Predicted to enable copper ion binding activity. Predicted to contribute to cytochrome-c oxidase activity. Involved in lactation and response to hypoxia. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex IV. Biomarker of acute myocardial infarction; colorectal carcinoma; and type 2 diabetes mellitus. Orthologous to several human genes including MT-CO2 (mitochondrially encoded cytochrome c oxidase II); INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR22888
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensMT-CO210 of 10YesYes  
Homo sapiensMTCO2P129 of 10NoYes  
Mus musculusmt-Co29 of 9YesYes   
Danio reriomt-co29 of 9YesYes   
Drosophila melanogastermt:CoII9 of 9YesYes   
Saccharomyces cerevisiaeCOX29 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

No paralogs for the gene.

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
7.1k7.2k7.3k7.4k7.5k7.6kENSRNOT00000043693.3 (Mt-co2)

Sequence Details

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Expression

Primary Sources
None
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

3 interactor genes based on 3 annotations
Mt-co2 molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
Itm2bRattus norvegicus
protein
  • affinity chromatography technology
PMID:29476059
protein
RNF207Homo sapiens
protein
  • affinity chromatography technology
PMID:35352799
protein
Sumo3Rattus norvegicus
protein
  • affinity chromatography technology
PMID:22082260
Showing 1 - 3 of 3 rows
per page

Genetic Interactions

No data available