Predicted to enable sphinganine-1-phosphate aldolase activity. Predicted to be involved in apoptotic signaling pathway; fatty acid metabolic process; and sphingolipid metabolic process. Predicted to act upstream of or within several processes, including face morphogenesis; gonad development; and steroid metabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in nephrotic syndrome type 14. Orthologous to human SGPL1 (sphingosine-1-phosphate lyase 1).
RGD Description
Predicted to enable sphinganine-1-phosphate aldolase activity. Predicted to be involved in apoptotic signaling pathway; fatty acid metabolic process; and sphingolipid metabolic process. Predicted to act upstream of or within several processes, including face morphogenesis; gonad development; and vasculogenesis. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in nephrotic syndrome type 14. Orthologous to human SGPL1 (sphingosine-1-phosphate lyase 1); PARTICIPATES IN Fabry disease pathway; Gaucher's disease pathway; Krabbe disease pathway; INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.