Gene

Pde1a

Species
Rattus norvegicus
Symbol
Pde1a
Name
phosphodiesterase 1A
Synonyms
  • 3-RACE clone 8 phosphodiesterase 1A
  • 3-RACEclone8phosphodiesterase1A
Biotype
protein coding gene
Automated Description
Enables calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity. Involved in cGMP catabolic process; regulation of smooth muscle cell apoptotic process; and regulation of smooth muscle cell proliferation. Located in neuronal cell body. Orthologous to human PDE1A (phosphodiesterase 1A).
RGD Description
Enables calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity. Involved in cGMP catabolic process; regulation of smooth muscle cell apoptotic process; and regulation of smooth muscle cell proliferation. Located in neuronal cell body. Orthologous to human PDE1A (phosphodiesterase 1A); PARTICIPATES IN protein kinase A (PKA) signaling pathway; calcium/calcium-mediated signaling pathway; purine metabolic pathway; INTERACTS WITH 3',5'-cyclic GMP; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11347
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
64.75M64.80M64.85M64.90M64.95M65.00M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions