Gene

Pttg1

Species
Rattus norvegicus
Symbol
Pttg1
Name
PTTG1 regulator of sister chromatid separation, securin
Synonyms
  • Pituitary tumor transforming
  • Pituitary tumor transforming gene
Biotype
protein coding gene
Automated Description
Enables heat shock protein binding activity and ribosome binding activity. Involved in negative regulation of cell population proliferation and regulation of cell growth. Predicted to be located in cytosol. Predicted to be active in axoneme and nucleus. Orthologous to several human genes including PTTG1 (PTTG1 regulator of sister chromatid separation, securin) and PTTG3P (pituitary tumor-transforming 3, pseudogene).
RGD Description
Enables heat shock protein binding activity and ribosome binding activity. Involved in negative regulation of cell population proliferation and regulation of cell growth. Predicted to be located in cytosol. Predicted to be active in axoneme and nucleus. Orthologous to several human genes including PTTG1 (PTTG1 regulator of sister chromatid separation, securin) and PTTG3P (pituitary tumor-transforming 3, pseudogene); PARTICIPATES IN cell cycle pathway, mitotic; INTERACTS WITH 1,3-dinitrobenzene; 1-naphthyl isothiocyanate; 17beta-estradiol.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10418
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
27.894M27.896M27.898M27.900M27.902M27.904M

Sequence Details

Loading...

Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions