Version: 8.1.0Date: Fri Apr 18 2025
Gene
Il13
- Species
- Rattus norvegicus
- Symbol
- Il13
- Name
- interleukin 13
- Synonyms
- IL-13
- interleukin-13
- Biotype
- protein coding gene
- Automated Description
- Enables interleukin-13 receptor binding activity. Involved in several processes, including positive regulation of cell population proliferation; regulation of gene expression; and regulation of monoatomic cation transmembrane transport. Located in extracellular space. Used to study asthma; extrinsic allergic alveolitis; and lipoid nephrosis. Biomarker of several diseases, including alcoholic hepatitis; middle cerebral artery infarction; peptic esophagitis; prostatic hypertrophy; and pulmonary fibrosis. Human ortholog(s) of this gene implicated in several diseases, including allergic disease (multiple); autoimmune disease (multiple); diffuse scleroderma; lung disease (multiple); and nose disease (multiple). Orthologous to human IL13 (interleukin 13).
- RGD Description
- Enables interleukin-13 receptor binding activity. Involved in several processes, including positive regulation of cell population proliferation; regulation of gene expression; and regulation of monoatomic cation transmembrane transport. Located in extracellular space. Used to study asthma; extrinsic allergic alveolitis; and lipoid nephrosis. Biomarker of several diseases, including alcoholic hepatitis; middle cerebral artery infarction; peptic esophagitis; prostatic hypertrophy; and pulmonary fibrosis. Human ortholog(s) of this gene implicated in several diseases, including allergic disease (multiple); autoimmune disease (multiple); diffuse scleroderma; lung disease (multiple); and nose disease (multiple). Orthologous to human IL13 (interleukin 13); PARTICIPATES IN Fc epsilon receptor mediated signaling pathway; asthma pathway; cytokine mediated signaling pathway; INTERACTS WITH 3-chloropropane-1,2-diol; acrylamide; ammonium chloride.
- Cross References
- Additional Information
- Literature
Orthology
- Gene tree
- PANTHER:PTHR48486
Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse
Phenotypes
- Primary Sources
- None
- Other Sources
- None
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Disease Associations
Cases where the expected disease association was NOT found
Cell color indicative of annotation volume
Alleles and Variants
Allele/Variant Symbol | Allele Synonyms | Category | Variant | Variant type | Molecular consequence | Has Disease Annotations | Has Phenotype Annotations |
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Transgenic Alleles
Species (carrying the transgene) | Allele symbol | Transgenic construct | Expressed components | Knock-down targets | Regulatory regions | Has Disease Annotations | Has Phenotype Annotations |
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Models
Model name | Experimental condition | Associated Human Diseases | Associated Phenotypes | Modifier | Source |
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Sequence Feature Viewer
- Genome location
- Chr10:37790130...37792737 - (2.61 kb)
- Assembly version
- mRatBN7.2
- Viewer Help
Data currently unavailable; sequence viewer under construction
Expression
- Primary Sources
- None
- Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.