Version: 8.0.0
Date: Tue Jan 28 2025
Tmed2
Rattus norvegicusRGD:69243
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Tmed2

Species
Rattus norvegicus
Symbol
Tmed2
Name
transmembrane p24 trafficking protein 2
Synonyms
  • coated vesicle membrane protein
  • COPI-coated vesicle membrane protein p24
Biotype
protein coding gene
Automated Description
Predicted to enable frizzled binding activity and smoothened binding activity. Predicted to be involved in several processes, including labyrinthine layer blood vessel development; maternal placenta development; and negative regulation of GTPase activity. Predicted to act upstream of or within several processes, including chordate embryonic development; regulation of gene expression; and regulation of signal transduction. Located in COPI-coated vesicle and zymogen granule membrane. Orthologous to human TMED2 (transmembrane p24 trafficking protein 2).
RGD Description
Predicted to enable frizzled binding activity and smoothened binding activity. Predicted to be involved in several processes, including labyrinthine layer blood vessel development; maternal placenta development; and negative regulation of GTPase activity. Predicted to act upstream of or within several processes, including chordate embryonic development; regulation of gene expression; and regulation of signal transduction. Located in COPI-coated vesicle and zymogen granule membrane. Orthologous to human TMED2 (transmembrane p24 trafficking protein 2); INTERACTS WITH 2-ethoxyethanol; 2-methoxyethanol; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR22811
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
References
No records match query. Try removing filters.
Showing 0 - 0 of 0 rows
per page

    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    No data available

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
    No records match query. Try removing filters.
    Showing 0 - 0 of 0 rows
    per page
      Download all Alleles/Variants for all genes of the species

      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
      Has Disease Annotations
      Has Phenotype Annotations
      No records match query. Try removing filters.
      Showing 0 - 0 of 0 rows
      per page

        Models

        Model name
        Experimental condition
        Associated Human Diseases
        Associated Phenotypes
        Modifier
        Source
        No records match query. Try removing filters.
        Showing 0 - 0 of 0 rows
        per page

          Sequence Feature Viewer

          Genome location
          Assembly version
          mRatBN7.2
          Viewer Help
          Data currently unavailable; sequence viewer under construction

          Sequence Details

          Loading...

          Expression

          Primary Sources
          None
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          Tmed2 molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection methods
          Source
          Reference
          No records match query. Try removing filters.
          Showing 0 - 0 of 0 rows
          per page

            Genetic Interactions

            Tmed2 role
            Tmed2 genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
            Source
            Reference
            No records match query. Try removing filters.
            Showing 0 - 0 of 0 rows
            per page