Gene

Mertk

Species
Rattus norvegicus
Symbol
Mertk
Name
MER proto-oncogene, tyrosine kinase
Synonyms
  • c-mer proto-oncogene tyrosine kinase
  • proto-oncogene c-Mer
Biotype
protein coding gene
Automated Description
Predicted to enable transmembrane receptor protein tyrosine kinase activity. Involved in phagocytosis; positive regulation of phagocytosis; and protein phosphorylation. Located in photoreceptor outer segment. Used to study retinal degeneration. Human ortholog(s) of this gene implicated in retinitis pigmentosa 38. Orthologous to human MERTK (MER proto-oncogene, tyrosine kinase).
RGD Description
Predicted to enable transmembrane receptor protein tyrosine kinase activity. Involved in phagocytosis; positive regulation of phagocytosis; and protein phosphorylation. Located in photoreceptor outer segment. Used to study retinal degeneration. Human ortholog(s) of this gene implicated in retinitis pigmentosa 38. Orthologous to human MERTK (MER proto-oncogene, tyrosine kinase); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24416
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
115.94M115.95M115.96M115.97M115.98M115.99M116.00M116.01M116.02M116.03M116.04M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions