Version: 8.0.0
Date: Tue Jan 28 2025
Fabp4
Rattus norvegicusRGD:69309
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Fabp4

Species
Rattus norvegicus
Symbol
Fabp4
Name
fatty acid binding protein 4
Synonyms
  • A-FABP
  • adipocyte lipid-binding protein
Biotype
protein coding gene
Automated Description
Predicted to enable hormone receptor binding activity; long-chain fatty acid binding activity; and long-chain fatty acid transmembrane transporter activity. Involved in several processes, including fatty acid metabolic process; response to glucocorticoid; and response to gravity. Predicted to be located in cytoplasm. Predicted to be active in cytosol and nucleus. Biomarker of impotence and muscular atrophy. Orthologous to human FABP4 (fatty acid binding protein 4).
RGD Description
Predicted to enable hormone receptor binding activity; long-chain fatty acid binding activity; and long-chain fatty acid transmembrane transporter activity. Involved in several processes, including fatty acid metabolic process; response to glucocorticoid; and response to gravity. Predicted to be located in cytoplasm. Predicted to be active in cytosol and nucleus. Biomarker of impotence and muscular atrophy. Orthologous to human FABP4 (fatty acid binding protein 4); PARTICIPATES IN eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma; INTERACTS WITH 1,2-dimethylhydrazine; 1,3,5-trinitro-1,3,5-triazinane; 1-naphthyl isothiocyanate.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11955
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    Gene
    Association
    Disease Qualifier
    Disease
    Evidence
    Source
    Based On
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
      Category
      Variant
      Variant type
      Molecular consequence
      Has Disease Annotations
      Has Phenotype Annotations
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
        Has Disease Annotations
        Has Phenotype Annotations
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          Models

          Model name
          Experimental condition
          Associated Human Diseases
          Associated Phenotypes
          Modifier
          Source
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            Sequence Feature Viewer

            Genome location
            Assembly version
            mRatBN7.2
            Viewer Help
            91.5810M91.5815M91.5820M91.5825M91.5830M91.5835M91.5840M91.5845M91.5850M91.5855M

            Sequence Details

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            Expression

            Primary Sources
            None
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            Fabp4 molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
            Detection methods
            Source
            Reference
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              Genetic Interactions

              Fabp4 role
              Fabp4 genetic perturbation
              Interactor gene
              Interactor species
              Interactor role
              Interactor genetic perturbation
              Interaction type
              Phenotype or trait
              Source
              Reference
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