Version: 8.0.0
Date: Tue Jan 28 2025
Prokr2
Rattus norvegicusRGD:708445
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Prokr2

Species
Rattus norvegicus
Symbol
Prokr2
Name
prokineticin receptor 2
Synonyms
  • G protein-coupled receptor 73-like 1
  • G protein-coupled receptor I5E
Biotype
protein coding gene
Automated Description
Enables G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway; cellular response to hormone stimulus; and circadian rhythm. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 3 with or without anosmia. Orthologous to human PROKR2 (prokineticin receptor 2).
RGD Description
Enables G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and circadian rhythm. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 3 with or without anosmia. Orthologous to human PROKR2 (prokineticin receptor 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24238
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensPROKR210 of 10YesYes☑☑☑☑☑☑☑☑☑☑  
Mus musculusProkr29 of 9YesYes☑ ☑☑☑☑☑☑☑☑  
Xenopus tropicalisprokr28 of 9YesYes☑ ☑☑☑☑☑☑☑☐  
Danio rerioprokr1b9 of 9YesYes☑ ☑☑☑☑☑☑☑☑  
Danio rerioprokr1a6 of 9NoYes☑ ☐☐☑☑☐☑☑☑  
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
Prokr1138889797 of 9☑☐☑☐☑☑☑☑☑ 
Npffr2242643242 of 9☐☐☐☐☐☐☑☑☐ 
Hcrtr1342142262 of 9☐☐☐☐☐☐☑☑☐ 
Hcrtr2437846272 of 9☐☐☐☐☐☐☑☑☐ 
Avpr2540942242 of 9☐☐☐☐☐☐☑☑☐ 
Pgr15l735549262 of 9☑☐☐☐☐☐☐☑☐ 
Prlhr830255312 of 9☑☐☐☐☐☐☐☑☐ 
Npy2r931254282 of 9☑☐☐☐☐☐☐☑☐ 
Tacr11032851272 of 9☑☐☐☐☐☐☐☑☐ 
Gpr831134247262 of 9☑☐☐☐☐☐☐☑☐ 
Mchr11235144272 of 9☑☐☐☐☐☐☐☑☐ 
Qrfpr1331950282 of 9☐☐☐☐☐☐☑☑☐ 
Npy1r1432350262 of 9☑☐☐☐☐☐☐☑☐ 
Tacr31532849262 of 9☑☐☐☐☐☐☐☑☐ 
Npy4r1631249262 of 9☑☐☐☐☐☐☐☑☐ 
Tacr21729450282 of 9☑☐☐☐☐☐☐☑☐ 
Cckar1833243252 of 9☐☐☐☐☐☐☑☑☐ 
Gnrhr1933343252 of 9☐☐☐☐☐☐☑☑☐ 
Oxtr2035741222 of 9☐☐☐☐☐☐☑☑☐ 
Mtnr1b2132944242 of 9☑☐☐☐☐☐☐☑☐ 
Avpr1a2229945272 of 9☐☐☐☐☐☐☑☑☐ 

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume
Species
Gene
Association
Disease Qualifier
Disease
Evidence
Source
Based On
References
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    Alleles and Variants

    Genome location
    Assembly version
    mRatBN7.2
    Viewer Help
    Data currently unavailable; sequence viewer under construction
    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
    NC_051338.1:g.119632575C>Tvariant
    SNP
    • intron variant
    NC_051338.1:g.119634050C>Avariant
    SNP
    • intron variant
    NC_051338.1:g.119626328A>Gvariant
    SNP
    • 3 prime UTR variant
    NC_051338.1:g.119627482A>Tvariant
    SNP
    • 3 prime UTR variant
    NC_051338.1:g.119628489C>Tvariant
    SNP
    • intron variant
    NC_051338.1:g.119628581A>Gvariant
    SNP
    • intron variant
    NC_051338.1:g.119626561T>Cvariant
    SNP
    • 3 prime UTR variant
    NC_051338.1:g.119627793A>Gvariant
    SNP
    • synonymous variant
    NC_051338.1:g.119631709G>Tvariant
    SNP
    • intron variant
    NC_051338.1:g.119638818C>Tvariant
    SNP
    • intron variant
    Showing 1 - 10 of 34 rows
    per page
    View detailed Alleles/Variants information
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    Transgenic Alleles

    No data available

    Models

    No data available

    Sequence Feature Viewer

    Genome location
    Assembly version
    mRatBN7.2
    Viewer Help
    Data currently unavailable; sequence viewer under construction

    Sequence Details

    Transcript: Mode:

    Expression

    Primary Sources
    None
    Other Sources
    Must provide at least one subject
    Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

    Molecular Interactions

    No data available

    Genetic Interactions

    No data available