Version: 8.0.0
Date: Tue Jan 28 2025
Ugt1a8
Rattus norvegicusRGD:708474
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Ugt1a8

Species
Rattus norvegicus
Symbol
Ugt1a8
Name
UDP glucuronosyltransferase family 1 member A8
Synonyms
  • A3
  • UDP glycosyltransferase 1 family, polypeptide A8
Biotype
protein coding gene
Automated Description
Enables glucuronosyltransferase activity. Involved in cellular response to organic cyclic compound and coumarin catabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in alcoholic pancreatitis and pancreatic cancer. Orthologous to several human genes including UGT1A8 (UDP glucuronosyltransferase family 1 member A8).
RGD Description
Enables glucuronosyltransferase activity. Involved in cellular response to organic cyclic compound and coumarin catabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in alcoholic pancreatitis and pancreatic cancer. Orthologous to several human genes including UGT1A8 (UDP glucuronosyltransferase family 1 member A8); PARTICIPATES IN codeine and morphine pharmacodynamics pathway; codeine and morphine pharmacokinetics pathway; mycophenolic acid pharmacokinetics pathway; INTERACTS WITH 1-naphthol; 17alpha-ethynylestradiol; 17beta-estradiol.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR48043
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
Ugt1a7c153193896 of 9☐☐☑☐☑☑☑☑☑ 
Ugt1a1253677686 of 9☐☐☑☐☑☑☑☑☑ 
Ugt1a2353177686 of 9☐☐☑☐☑☑☑☑☑ 
Ugt1a6452578686 of 9☐☐☑☐☑☑☑☑☑ 
Ugt1a5552178696 of 9☐☐☑☐☑☑☑☑☑ 
Ugt1a3653575666 of 9☐☐☑☐☑☑☑☑☑ 
Ugt2b34l1754562455 of 9☐☐☑☐☑☑☐☑☑ 
Ugt2a3854259445 of 9☐☐☑☐☑☑☐☑☑ 
Ugt2b1952462445 of 9☐☐☑☐☑☑☐☑☑ 
Ugt2b371054060425 of 9☐☐☑☐☑☑☐☑☑ 
Ugt2b151153660435 of 9☐☐☑☐☑☑☐☑☑ 
Ugt2b351255756415 of 9☐☐☑☐☑☑☐☑☑ 
Ugt2b71352960445 of 9☐☐☑☐☑☑☐☑☑ 
Ugt2b1452961435 of 9☐☐☑☐☑☑☐☑☑ 
Ugt2a11552460435 of 9☐☐☑☐☑☑☐☑☑ 
Ugt81655253345 of 9☐☐☑☐☑☑☐☑☑ 
Ugt3a11743748315 of 9☐☐☑☐☑☑☐☑☑ 

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume
No data available

Alleles and Variants

Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
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    Transgenic Alleles

    No data available

    Models

    No data available

    Sequence Feature Viewer

    Genome location
    Assembly version
    mRatBN7.2
    Viewer Help
    Data currently unavailable; sequence viewer under construction

    Sequence Details

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    Expression

    Primary Sources
    None
    Other Sources
    Must provide at least one subject
    Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

    Molecular Interactions

    No data available

    Genetic Interactions

    No data available