Gene

Akr1b8

Species
Rattus norvegicus
Symbol
Akr1b8
Name
aldo-keto reductase family 1, member B8
Synonyms
  • aldose reductase-like protein
  • aldose reductase-related protein 2
Biotype
protein coding gene
Automated Description
Predicted to enable estradiol 17-beta-dehydrogenase [NAD(P)+] activity. Predicted to be located in cytosol and mitochondrion. Orthologous to human AKR1B10 (aldo-keto reductase family 1 member B10).
RGD Description
Predicted to enable aldose reductase (NADPH) activity and estradiol 17-beta-dehydrogenase [NAD(P)+] activity. Predicted to be located in mitochondrion. Predicted to be active in cytosol. Orthologous to human AKR1B10 (aldo-keto reductase family 1 member B10); INTERACTS WITH bisphenol A; 2-palmitoylglycerol (ortholog); 4-nitrobenzaldehyde (ortholog).
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11732
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
62.998M63.000M63.002M63.004M63.006M63.008M63.010M

Sequence Details

Loading...

Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions