Gene

Riox2

Species
Rattus norvegicus
Symbol
Riox2
Name
ribosomal oxygenase 2
Synonyms
  • bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA
  • histone lysine demethylase MINA
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including histone H3 demethylase activity; identical protein binding activity; and peptidyl-histidine dioxygenase activity. Predicted to be involved in chromatin remodeling; negative regulation of DNA-templated transcription; and ribosome biogenesis. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of transcription regulator complex. Predicted to be active in nucleolus. Orthologous to human RIOX2 (ribosomal oxygenase 2).
RGD Description
Predicted to enable several functions, including histone H3 demethylase activity; identical protein binding activity; and peptidyl-histidine dioxygenase activity. Predicted to be involved in chromatin remodeling; negative regulation of DNA-templated transcription; and ribosome biogenesis. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of transcription regulator complex. Predicted to be active in nucleolus. Orthologous to human RIOX2 (ribosomal oxygenase 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 4-amino-2,6-dinitrotoluene.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13096
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensRIOX210 of 10YesYes  
Mus musculusRiox29 of 9YesYes   
Xenopus tropicalisriox29 of 9YesYes   
Danio rerioriox29 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
Riox1148150333 of 9 

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Alleles and Variants

Genome location
Assembly version
mRatBN7.2
Viewer Help
40.862M40.864M40.866M40.868M40.870M40.872M40.874M40.876M40.878M40.880M40.882M40.884M
Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
NC_051346.1:g.40867809C>Gvariant
SNP
  • intron variant
NC_051346.1:g.40868492G>Avariant
SNP
  • intron variant
NC_051346.1:g.40871732G>Avariant
SNP
  • intron variant
NC_051346.1:g.40871817G>Avariant
SNP
  • intron variant
NC_051346.1:g.40875484G>Avariant
SNP
  • intron variant
NC_051346.1:g.40880672C>Tvariant
SNP
  • intron variant
NC_051346.1:g.40868561A>Gvariant
SNP
  • intron variant
NC_051346.1:g.40874669G>Avariant
SNP
  • intron variant
NC_051346.1:g.40876533C>Tvariant
SNP
  • intron variant
NC_051346.1:g.40880668C>Tvariant
SNP
  • intron variant
Showing 1 - 10 of 165 rows
per page

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
40.862M40.864M40.866M40.868M40.870M40.872M40.874M40.876M40.878M40.880M40.882M40.884M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

No data available

Genetic Interactions

No data available