Gene

Prdx5

Species
Rattus norvegicus
Symbol
Prdx5
Name
peroxiredoxin 5
Synonyms
  • antioxidant enzyme B166
  • Aoeb166
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including cysteine-type endopeptidase inhibitor activity involved in apoptotic process; identical protein binding activity; and peroxidase activity. Predicted to be involved in several processes, including NADPH oxidation; cell redox homeostasis; and regulation of apoptotic process. Located in mitochondrion and peroxisome. Orthologous to human PRDX5 (peroxiredoxin 5).
RGD Description
Predicted to enable several functions, including cysteine-type endopeptidase inhibitor activity involved in apoptotic process; identical protein binding activity; and peroxidase activity. Predicted to be involved in several processes, including NADPH oxidation; cell redox homeostasis; and regulation of apoptotic process. Located in mitochondrion and peroxisome. Orthologous to human PRDX5 (peroxiredoxin 5); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3-bis(4-hydroxyphenyl)propionitrile.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10430
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensPRDX510 of 10YesYes  
Mus musculusPrdx59 of 9YesYes   
Xenopus tropicalisprdx55 of 9YesYes   
Danio rerioprdx59 of 9YesYes   
Drosophila melanogasterPrx59 of 9YesYes   
Saccharomyces cerevisiaeAHP15 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

No paralogs for the gene.

Function - GO Annotations

No function available for that gene

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Alleles and Variants

Genome location
Assembly version
mRatBN7.2
Viewer Help
204.100M204.102M204.104M204.106M204.108M204.110M204.112M204.114M
Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
NC_051336.1:g.204099922C>Tvariant
SNP
  • 3 prime UTR variant
NC_051336.1:g.204100153A>Gvariant
SNP
  • intron variant
NC_051336.1:g.204104128C>Tvariant
SNP
  • 3 prime UTR variant
NC_051336.1:g.204104400G>Avariant
SNP
  • 3 prime UTR variant
NC_051336.1:g.204108908C>Tvariant
NC_051336.1:g.204109011G>Avariant
SNP
  • intron variant
NC_051336.1:g.204110261C>Tvariant
SNP
  • intron variant
NC_051336.1:g.204111020G>Avariant
SNP
  • intron variant
NC_051336.1:g.204113453G>Cvariant
NC_051336.1:g.204113930A>Tvariant
SNP
  • intron variant
Showing 1 - 10 of 38 rows
per page

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
204.100M204.102M204.104M204.106M204.108M204.110M204.112M204.114MENSRNOT00000028687.4 (Prdx5)ENSRNOT00000104624.1 (Prdx5)ENSRNOT00000110859.1 (Prdx5)ENSRNOT00000111281.1 (Prdx5)NM_053610.1 (Prdx5)XM_039105128.2 (Prdx5)XM_039105162.2 (Prdx5)XM_039105211.2 (Prdx5)XM_039105308.2 (Prdx5)NM_001106330.2 (Trmt112)Maximum features displayed. See full view for more.

Sequence Details

Transcript: Mode:

Expression

Primary Sources
None
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

2 interactor genes based on 3 annotations
Prdx5 molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
Gja1Rattus norvegicus
protein
  • affinity chromatography technology
PMID:23106098
protein
Gja1Rattus norvegicus
protein
  • affinity chromatography technology
PMID:26316108
protein
MaptRattus norvegicus
protein
  • affinity chromatography technology
PMID:32357304
Showing 1 - 3 of 3 rows
per page

Genetic Interactions

No data available