Gene

Txn2

Species
Rattus norvegicus
Symbol
Txn2
Name
thioredoxin 2
Synonyms
  • MGC93312
  • mt-Trx
Biotype
protein coding gene
Automated Description
Contributes to peptide-methionine (R)-S-oxide reductase activity; peptide-methionine (S)-S-oxide reductase activity; and protein-disulfide reductase activity. Involved in several processes, including response to axon injury; response to glucose; and response to hypoxia. Located in dendrite and neuronal cell body. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 29. Orthologous to human TXN2 (thioredoxin 2).
RGD Description
Contributes to peptide-methionine (R)-S-oxide reductase activity; peptide-methionine (S)-S-oxide reductase activity; and protein-disulfide reductase activity. Involved in several processes, including response to axon injury; response to glucose; and response to hypoxia. Located in dendrite and neuronal cell body. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 29. Orthologous to human TXN2 (thioredoxin 2); INTERACTS WITH 1,1'-azobis(N,N-dimethylformamide); 4,4'-sulfonyldiphenol; acrylamide.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR43601
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
109.498M109.500M109.502M109.504M109.506M109.508M109.510M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions