Gene

Fgf20

Species
Rattus norvegicus
Symbol
Fgf20
Name
fibroblast growth factor 20
Synonyms
  • FGF-20
  • Fgf4a
Biotype
protein coding gene
Automated Description
Enables fibroblast growth factor receptor binding activity and growth factor activity. Acts upstream of or within fibroblast growth factor receptor signaling pathway; positive regulation of ERK1 and ERK2 cascade; and positive regulation of cell population proliferation. Predicted to be active in cytoplasm and extracellular space. Human ortholog(s) of this gene implicated in renal agenesis. Orthologous to human FGF20 (fibroblast growth factor 20).
RGD Description
Enables fibroblast growth factor receptor binding activity and growth factor activity. Acts upstream of or within fibroblast growth factor receptor signaling pathway; positive regulation of ERK1 and ERK2 cascade; and positive regulation of cell population proliferation. Predicted to be active in cytoplasm and extracellular space. Human ortholog(s) of this gene implicated in renal agenesis. Orthologous to human FGF20 (fibroblast growth factor 20); PARTICIPATES IN melanoma pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH ammonium chloride; bisphenol A; chlorpyrifos.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11486
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
52.015M52.020M52.025M52.030M52.035M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions