Gene

Kiss1

Species
Rattus norvegicus
Symbol
Kiss1
Name
KiSS-1 metastasis-suppressor
Synonyms
  • eseptin
  • Kiss1 variant E1a-E2b-E3
Biotype
protein coding gene
Automated Description
Enables kisspeptin receptor binding activity. Involved in several processes, including generation of ovulation cycle rhythm; phospholipase C-activating G protein-coupled receptor signaling pathway; and positive regulation of cell communication. Located in apical plasma membrane; extracellular space; and neuronal cell body. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 13 with or without anosmia. Orthologous to human KISS1 (KiSS-1 metastasis suppressor).
RGD Description
Enables kisspeptin receptor binding activity. Involved in several processes, including generation of ovulation cycle rhythm; phospholipase C-activating G protein-coupled receptor signaling pathway; and positive regulation of cell communication. Located in apical plasma membrane; extracellular space; and neuronal cell body. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 13 with or without anosmia. Orthologous to human KISS1 (KiSS-1 metastasis suppressor); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR16955
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
44.775M44.776M44.777M44.778M44.779M44.780M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions