Gene

Psat1

Species
Rattus norvegicus
Symbol
Psat1
Name
phosphoserine aminotransferase 1
Synonyms
  • phosphoserine aminotransferase
  • Psa1
Biotype
protein coding gene
Automated Description
Predicted to enable O-phospho-L-serine:2-oxoglutarate aminotransferase activity; identical protein binding activity; and pyridoxal phosphate binding activity. Predicted to be involved in L-serine biosynthetic process. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in Neu-Laxova syndrome 2 and PSAT deficiency. Orthologous to human PSAT1 (phosphoserine aminotransferase 1).
RGD Description
Predicted to enable O-phospho-L-serine:2-oxoglutarate aminotransferase activity; identical protein binding activity; and pyridoxal phosphate binding activity. Predicted to be involved in L-serine biosynthetic process. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in Neu-Laxova syndrome 2 and PSAT deficiency. Orthologous to human PSAT1 (phosphoserine aminotransferase 1); PARTICIPATES IN dihydropyrimidine dehydrogenase deficiency pathway; dimethylglycine dehydrogenase deficiency pathway; nonketotic hyperglycinemia pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR43247
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensPSAT110 of 10YesYes  
Mus musculusPsat19 of 9YesYes   
Xenopus tropicalispsat14 of 9YesYes   
Danio reriopsat19 of 9YesYes   
Drosophila melanogasterPsat9 of 9YesYes   
Caenorhabditis elegansF26H9.59 of 9YesYes   
Saccharomyces cerevisiaeSER19 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
Agxt142234172 of 9 

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Alleles and Variants

Genome location
Assembly version
mRatBN7.2
Viewer Help
213.198M213.200M213.202M213.204M213.206M213.208M213.210M213.212M213.214M213.216M213.218M
Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
NC_051336.1:g.213207721G>Avariant
SNP
  • synonymous variant
NC_051336.1:g.213211083C>Avariant
SNP
  • intron variant
NC_051336.1:g.213212317C>Tvariant
SNP
  • intron variant
NC_051336.1:g.213215129C>Tvariant
SNP
  • intron variant
NC_051336.1:g.213215313A>Gvariant
SNP
  • intron variant
NC_051336.1:g.213203398G>Tvariant
SNP
  • intron variant
NC_051336.1:g.213209037A>Tvariant
SNP
  • intron variant
NC_051336.1:g.213210245G>Avariant
SNP
  • intron variant
NC_051336.1:g.213196885A>Gvariant
SNP
  • 3 prime UTR variant
NC_051336.1:g.213197525A>Gvariant
SNP
  • 3 prime UTR variant
Showing 1 - 10 of 174 rows
per page

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
213.198M213.200M213.202M213.204M213.206M213.208M213.210M213.212M213.214M213.216M213.218M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

1 interactor gene based on 1 annotation
Psat1 molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
UbcRattus norvegicus
protein
  • affinity chromatography technology
PMID:22871113
Showing 1 - 1 of 1 rows
per page

Genetic Interactions

No data available