Enables pyruvate kinase activity. Involved in glycolytic process. Located in cytoplasm. Orthologous to human PKM (pyruvate kinase M1/2).
SGD Description
Pyruvate kinase; functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvate, the input for aerobic (TCA cycle) or anaerobic (glucose fermentation) respiration; regulated via allosteric activation by fructose bisphosphate; CDC19 has a paralog, PYK2, that arose from the whole genome duplication