Gene

UGA2

Species
Saccharomyces cerevisiae
Symbol
UGA2
Name
Utilization of GAba
Synonyms
  • UGA5
  • YBR006W
Biotype
protein coding gene
Automated Description
Enables succinate-semialdehyde dehydrogenase [NAD(P)+] activity. Involved in cellular response to oxidative stress; gamma-aminobutyrate shunt; and gamma-aminobutyric acid catabolic process. Located in cytoplasm. Human ortholog(s) of this gene implicated in succinic semialdehyde dehydrogenase deficiency. Orthologous to human ALDH5A1 (aldehyde dehydrogenase 5 family member A1).
SGD Description
Succinate semialdehyde dehydrogenase; involved in the utilization of gamma-aminobutyrate (GABA) as a nitrogen source; part of the 4-aminobutyrate and glutamate degradation pathways; localized to the cytoplasm
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR43353:SF5
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
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247.2k247.4k247.6k247.8k248.0k248.2k248.4k

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions