Version: 8.0.0
Date: Tue Jan 28 2025
FAT1
Saccharomyces cerevisiaeSGD:S000000245
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

FAT1

Species
Saccharomyces cerevisiae
Symbol
FAT1
Name
FATty acid transporter
Synonyms
  • YBR041W
Biotype
protein coding gene
Automated Description
Enables long-chain fatty acid transmembrane transporter activity and very long-chain fatty acid-CoA ligase activity. Involved in long-chain fatty acid import into cell; protein quality control for misfolded or incompletely synthesized proteins; and very long-chain fatty acid metabolic process. Located in several cellular components, including cytoplasmic side of plasma membrane; lipid droplet; and peroxisome. Orthologous to several human genes including SLC27A1 (solute carrier family 27 member 1); SLC27A2 (solute carrier family 27 member 2); and SLC27A3 (solute carrier family 27 member 3).
SGD Description
Very long chain fatty acyl-CoA synthetase and fatty acid transporter; activates imported fatty acids with a preference for very long lengths (C20-C26); has a separate function in the transport of long chain fatty acids
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR43107:SF15
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    No data available

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
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      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
      Has Disease Annotations
      Has Phenotype Annotations
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        Models

        Model name
        Experimental condition
        Associated Human Diseases
        Associated Phenotypes
        Modifier
        Source
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          Sequence Feature Viewer

          Genome location
          Assembly version
          R64-5-1
          Viewer Help
          Data currently unavailable; sequence viewer under construction

          Sequence Details

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          Expression

          Primary Sources
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          FAT1 molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection methods
          Source
          Reference
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            Genetic Interactions

            FAT1 role
            FAT1 genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
            Source
            Reference
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