Gene

REB1

Species
Saccharomyces cerevisiae
Symbol
REB1
Name
RNA polymerase I Enhancer Binding protein
Synonyms
  • EBF1
  • GRF2
Biotype
protein coding gene
Automated Description
Enables sequence-specific DNA binding activity. Involved in regulation of transcription by RNA polymerase II; termination of RNA polymerase II transcription; and transcriptional start site selection at RNA polymerase II promoter. Located in nucleoplasm. Orthologous to human DMTF1 (cyclin D binding myb like transcription factor 1) and TTF1 (transcription termination factor 1).
SGD Description
RNA polymerase I enhancer binding protein; DNA binding protein that binds to genes transcribed by both RNA polymerase I and RNA polymerase II; required for termination of RNA polymerase I transcription; Reb1p bound to DNA acts to block RNA polymerase II readthrough transcription
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR46380:SF2
No data available
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Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    Gene
    Association
    Disease Qualifier
    Disease
    Evidence
    Source
    Based On
    References
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
      Category
      Variant
      Variant type
      Molecular consequence
      Has Disease Annotations
      Has Phenotype Annotations
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
        Has Disease Annotations
        Has Phenotype Annotations
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          Models

          Model name
          Experimental condition
          Associated Human Diseases
          Associated Phenotypes
          Modifier
          Source
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            Sequence Feature Viewer

            Genome location
            Assembly version
            R64-5-1
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            334.4k334.6k334.8k335.0k335.2k335.4k335.6k335.8k336.0k336.2k336.4k336.6k336.8k

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            REB1 molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
            Detection methods
            Source
            Reference
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              Genetic Interactions

              REB1 role
              REB1 genetic perturbation
              Interactor gene
              Interactor species
              Interactor role
              Interactor genetic perturbation
              Interaction type
              Phenotype or trait
              Source
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