Gene

PCA1

Species
Saccharomyces cerevisiae
Symbol
PCA1
Name
P-type Cation-transporting ATPase
Synonyms
  • CAD2
  • PAY2
Biotype
protein coding gene
Automated Description
Enables P-type cadmium transporter activity; copper ion binding activity; and proteasome binding activity. Involved in cadmium ion transport; intracellular monoatomic cation homeostasis; and transmembrane transport. Located in plasma membrane. Part of proteasome core complex.
SGD Description
Cadmium transporting P-type ATPase; may also have a role in copper and iron homeostasis; stabilized by Cd binding, which prevents ubiquitination; S288C and other lab strains contain a G970R mutation which eliminates Cd transport function
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR46594:SF4
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
Viewer Help
793.0k793.5k794.0k794.5k795.0k795.5k796.0k

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions