Gene

KCC4

Species
Saccharomyces cerevisiae
Symbol
KCC4
Name
Not Available
Synonyms
  • YCL024W
Biotype
protein coding gene
Automated Description
Enables protein kinase activity. Involved in budding cell bud growth; mitotic morphogenesis checkpoint signaling; and septin ring assembly. Located in cellular bud neck septin collar; incipient cellular bud site; and septin ring. Orthologous to human BRSK1 (BR serine/threonine kinase 1) and BRSK2 (BR serine/threonine kinase 2).
SGD Description
Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24343:SF307
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
Viewer Help
79.5k80.0k80.5k81.0k81.5k82.0k

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions