Gene

EDC3

Species
Saccharomyces cerevisiae
Symbol
EDC3
Name
Enhancer of mRNA DeCapping
Synonyms
  • DCP3
  • LSM16
Biotype
protein coding gene
Automated Description
Enables mRNA binding activity. Involved in P-body assembly; cellular response to glucose starvation; and regulation of gene expression. Located in P-body and nucleus. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 50. Orthologous to human EDC3 (enhancer of mRNA decapping 3).
SGD Description
Non-essential conserved protein with a role in mRNA decapping; specifically affects the function of the decapping enzyme Dcp1p; mediates decay of the RPS28B mRNA via binding to both Rps28Bp (or Rps28Ap) and the RPS28B mRNA; mediates decay of the YRA1 mRNA by a different, translation-independent mechanism; localizes to cytoplasmic mRNA processing bodies; forms cytoplasmic foci upon DNA replication stress
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13612:SF0
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
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Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions