Enables mRNA binding activity. Involved in P-body assembly; cellular response to glucose starvation; and regulation of gene expression. Located in P-body and nucleus. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 50. Orthologous to human EDC3 (enhancer of mRNA decapping 3).
SGD Description
Non-essential conserved protein with a role in mRNA decapping; specifically affects the function of the decapping enzyme Dcp1p; mediates decay of the RPS28B mRNA via binding to both Rps28Bp (or Rps28Ap) and the RPS28B mRNA; mediates decay of the YRA1 mRNA by a different, translation-independent mechanism; localizes to cytoplasmic mRNA processing bodies; forms cytoplasmic foci upon DNA replication stress