Gene

NUG1

Species
Saccharomyces cerevisiae
Symbol
NUG1
Name
NUclear GTPase
Synonyms
  • YER006W
Biotype
protein coding gene
Automated Description
Enables GTPase activity and RNA binding activity. Involved in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and ribosomal large subunit export from nucleus. Located in nucleolus. Part of preribosome, large subunit precursor. Orthologous to several human genes including GNL3 (G protein nucleolar 3).
SGD Description
GTPase that associates with nuclear 60S pre-ribosomes; required for export of 60S ribosomal subunits from the nucleus
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11089:SF30
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None
Phenotype Term
Annotation details
References
decreased competitive fitness
decreased protein/peptide accumulation
decreased resistance to chemicals
decreased vegetative growth
haploinsufficient
increased resistance to chemicals
inviable
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Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Transgenic Alleles

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
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162.8k163.0k163.2k163.4k163.6k163.8k164.0k164.2k

Sequence Details

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Expression

Primary Sources
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions