Enables GTPase activity and RNA binding activity. Involved in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and ribosomal large subunit export from nucleus. Located in nucleolus. Part of preribosome, large subunit precursor. Orthologous to several human genes including GNL3 (G protein nucleolar 3).
SGD Description
GTPase that associates with nuclear 60S pre-ribosomes; required for export of 60S ribosomal subunits from the nucleus