Version: 8.1.0Date: Fri Apr 18 2025
Gene
FAA2
- Species
- Saccharomyces cerevisiae
- Symbol
- FAA2
- Name
- Fatty Acid Activation
- Synonyms
- FAM1
- YER015W
- Biotype
- protein coding gene
- Automated Description
- Enables long-chain fatty acid-CoA ligase activity; medium-chain fatty acid-CoA ligase activity; and very long-chain fatty acid-CoA ligase activity. Involved in long-chain fatty acid metabolic process. Located in peroxisome. Human ortholog(s) of this gene implicated in acute myeloid leukemia; congenital diarrhea; and leukemia. Orthologous to several human genes including ACSL1 (acyl-CoA synthetase long chain family member 1) and ACSL5 (acyl-CoA synthetase long chain family member 5).
- SGD Description
- Medium chain fatty acyl-CoA synthetase; activates imported fatty acids; accepts a wide range of fatty acid chain lengths with a preference for medium chains, C9:0-C13:0; localized to the peroxisome; comparative analysis suggests that a mitochondrially targeted form may result from translation starting at a non-canonical codon upstream of the annotated start codon
- Cross References
- Additional Information
- Literature
Orthology
- Gene tree
- PANTHER:PTHR43272:SF33
Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse
Phenotypes
- Primary Sources
- Other Sources
- None
Phenotype Term | Annotation details | References |
|---|---|---|
| No records match query. Try removing filters. | ||
Showing 0 - 0 of 0 rows
per page
Disease Associations
Cases where the expected disease association was NOT found
Cell color indicative of annotation volume
Alleles and Variants
Allele/Variant Symbol | Allele Synonyms | Category | Variant | Variant type | Molecular consequence | Has Disease Annotations | Has Phenotype Annotations |
|---|---|---|---|---|---|---|---|
| No records match query. Try removing filters. | |||||||
Showing 0 - 0 of 0 rows
per page
Transgenic Alleles
Species (carrying the transgene) | Allele symbol | Transgenic construct | Expressed components | Knock-down targets | Regulatory regions | Has Disease Annotations | Has Phenotype Annotations |
|---|---|---|---|---|---|---|---|
| No records match query. Try removing filters. | |||||||
Showing 0 - 0 of 0 rows
per page
Models
Model name | Experimental condition | Associated Human Diseases | Associated Phenotypes | Modifier | Source |
|---|---|---|---|---|---|
| No records match query. Try removing filters. | |||||
Showing 0 - 0 of 0 rows
per page
Sequence Feature Viewer
- Genome location
- ChrV:184541...186775 + (2.23 kb)
- Assembly version
- R64-5-1
- Viewer Help
Data currently unavailable; sequence viewer under construction
Expression
- Primary Sources
- Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.