Version: 8.0.0Date: Tue Jan 28 2025
Gene
BMH1
- Species
- Saccharomyces cerevisiae
- Symbol
- BMH1
- Name
- Brain Modulosignalin Homolog
- Synonyms
- APR6
- YER177W
- Biotype
- protein coding gene
- Automated Description
- Enables DNA replication origin binding activity; RNA polymerase II-specific DNA-binding transcription factor binding activity; and phosphoserine residue binding activity. Involved in several processes, including aggresome assembly; intracellular signal transduction; and regulation of primary metabolic process. Located in cytoplasm and nucleus. Orthologous to human YWHAE (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon).
- SGD Description
- 14-3-3 protein, major isoform; involved in post-transcriptional control of the proteome; binds to both proteins and to DNA, including replication origins; regulates exocytosis, vesicle transport, Ras/MAPK and rapamycin-sensitive signaling, aggresome formation, the spindle position checkpoint and meiotic commitment; protein abundance and relative distribution to the nucleus increase upon DNA replication stress; antiapoptotic gene; similar to several human 14-3-3 proteins
- Cross References
- Additional Information
- Literature
Orthology
- Gene tree
- PANTHER:PTHR18860:SF31
Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse
Disease Associations
Cases where the expected disease association was NOT found
Cell color indicative of annotation volume
Sequence Feature Viewer
- Genome location
- ChrV:545611...546414 + (0.80 kb)
- Assembly version
- R64-5-1
- Viewer Help
Data currently unavailable; sequence viewer under construction