Gene

APE4

Species
Saccharomyces cerevisiae
Symbol
APE4
Name
Not Available
Synonyms
  • YHR113W
Biotype
protein coding gene
Automated Description
Enables aminopeptidase activity. Involved in proteolysis. Located in fungal-type vacuole lumen. Orthologous to human DNPEP (aspartyl aminopeptidase).
SGD Description
Cytoplasmic aspartyl aminopeptidase with possible vacuole function; targeted to vacuole via Vps10p-dependent endosomal vacuolar protein sorting pathway and via CVT pathway; cleaves unblocked N-terminal acidic amino acids from peptide substrates; forms 12-subunit homo-oligomer; M18 metalloprotease family
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR28570:SF3
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
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336.4k336.6k336.8k337.0k337.2k337.4k337.6k337.8k

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions