Gene

PFS1

Species
Saccharomyces cerevisiae
Symbol
PFS1
Name
Prospore Formation at Spindles
Synonyms
  • ADY1
  • YHR185C
Biotype
protein coding gene
Automated Description
Involved in ascospore wall assembly. Predicted to be located in cytoplasm; nucleus; and spindle pole body.
SGD Description
Sporulation protein required for prospore membrane formation; required for prospore membrane formation at selected spindle poles; ensures functionality of all four spindle pole bodies during meiosis II; not required for meiotic recombination or meiotic chromosome segregation
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

No paralogs for the gene.

Function - GO Annotations

No function available for that gene

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None
Phenotype Term
Annotation details
References
abnormal sporulation
abnormal vacuolar morphology
decreased hyperosmotic stress resistance
decreased rate utilization of nitrogen source
decreased resistance to chemicals
decreased sporulation
decreased sporulation efficiency
decreased toxin resistance
decreased vegetative growth
increased biofilm formation
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Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Alleles and Variants

Genome location
Assembly version
R64-5-1
Viewer Help
474.7k474.8k474.9k475.0k475.1k475.2k475.3k
Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
pfs1-Δ
  • pfs1-delta
allele
Yes
NC_001140.6:g.474819G>Avariant
SNP
  • synonymous variant
NC_001140.6:g.474959G>Tvariant
SNP
  • missense variant
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Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
Viewer Help
474.7k474.8k474.9k475.0k475.1k475.2k475.3k

Sequence Details

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Expression

Primary Sources
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions

PFS1 role
PFS1 genetic perturbation
Interactor gene
Interactor species
Interactor role
Interactor genetic perturbation
Interaction type
Phenotype or trait
Source
Reference
unspecified role
AIM45Saccharomyces cerevisiae
unspecified role
negative genetic interaction (sensu BioGRID)
  • colony size
PMID:27708008
unspecified role
ALG5Saccharomyces cerevisiae
unspecified role
negative genetic interaction (sensu BioGRID)
  • colony size
PMID:27708008
unspecified role
AOS1Saccharomyces cerevisiae
unspecified role
negative genetic interaction (sensu BioGRID)
  • colony size
PMID:27708008
unspecified role
ARP3Saccharomyces cerevisiae
unspecified role
negative genetic interaction (sensu BioGRID)
  • colony size
PMID:27708008
unspecified role
AXL1Saccharomyces cerevisiae
unspecified role
negative genetic interaction (sensu BioGRID)
  • colony size
PMID:20093466
unspecified role
BLM10Saccharomyces cerevisiae
unspecified role
negative genetic interaction (sensu BioGRID)
  • colony size
PMID:20093466
unspecified role
BLM10Saccharomyces cerevisiae
unspecified role
negative genetic interaction (sensu BioGRID)
  • colony size
PMID:27708008
unspecified role
CDC28Saccharomyces cerevisiae
unspecified role
dosage lethality (sensu BioGRID)
  • inviable
PMID:28428242
unspecified role
CDC50Saccharomyces cerevisiae
unspecified role
negative genetic interaction (sensu BioGRID)
  • colony size
PMID:27708008
unspecified role
CGR1Saccharomyces cerevisiae
unspecified role
negative genetic interaction (sensu BioGRID)
  • colony size
PMID:20093466
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