Gene

RPL40A

Species
Saccharomyces cerevisiae
Symbol
RPL40A
Name
Ribosomal Protein of the Large subunit
Synonyms
  • CEP52A
  • eL40
Biotype
protein coding gene
Automated Description
Predicted to enable protein tag activity and ubiquitin protein ligase binding activity. Involved in protein ubiquitination; ribosomal large subunit assembly; and ribosomal large subunit export from nucleus. Located in cytoplasm and nucleus. Part of cytosolic large ribosomal subunit. Orthologous to human UBA52 (ubiquitin A-52 residue ribosomal protein fusion product 1).
SGD Description
Ubiquitin-ribosomal 60S subunit protein L40A fusion protein; cleaved to yield ubiquitin and ribosomal protein L40A; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes; homologous to mammalian ribosomal protein L40, no bacterial homolog; RPL40A has a paralog, RPL40B, that arose from the whole genome duplication; relative distribution to the nucleus increases upon DNA replication stress
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10666:SF368
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
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68.8k68.9k69.0k69.1k69.2k69.3k69.4k69.5k

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions