Gene

MSL1

Species
Saccharomyces cerevisiae
Symbol
MSL1
Name
MUD Synthetic Lethal
Synonyms
  • YIB9
  • YIB9w
Biotype
protein coding gene
Automated Description
Enables U2 snRNA binding activity. Involved in mRNA splicing, via spliceosome. Part of U2-type prespliceosome. Human ortholog(s) of this gene implicated in connective tissue disease. Orthologous to human SNRPA (small nuclear ribonucleoprotein polypeptide A) and SNRPB2 (small nuclear ribonucleoprotein polypeptide B2).
SGD Description
U2B component of U2 snRNP; involved in splicing, binds the U2 snRNA stem-loop IV in vitro but requires association of Lea1p for in vivo binding; does not contain the conserved C-terminal RNA binding domain found in other family members
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10501:SF64
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
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374.55k374.60k374.65k374.70k374.75k374.80k374.85k

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions