Enables CAAX-protein geranylgeranyltransferase activity and protein farnesyltransferase activity. Involved in peptide pheromone maturation; protein farnesylation; and protein geranylgeranylation. Part of CAAX-protein geranylgeranyltransferase complex and protein farnesyltransferase complex. Orthologous to human FNTA (farnesyltransferase, CAAX box, subunit alpha).
SGD Description
Alpha subunit of farnesyltransferase and geranylgeranyltransferase-I; farnesyltransferase (Ram2p-Ram1p heterodimer) catalyzes the addition of 15-carbon isoprenoid farnesyl to substrate proteins containing a CAAX consensus motif; type I geranylgeranyltransferase (Ram2p-Cdc43p heterodimer) catalyzes the addition of the 20-carbon isoprenoid geranylgeranyl to substrate proteins containing a CaaL consensus motif; required for membrane localization of Ras proteins and a-factor