Gene

RPN12

Species
Saccharomyces cerevisiae
Symbol
RPN12
Name
Regulatory Particle Non-ATPase
Synonyms
  • NIN1
  • YFR052W
Biotype
protein coding gene
Automated Description
Involved in ubiquitin-dependent protein catabolic process. Located in proteasome storage granule. Part of proteasome regulatory particle, lid subcomplex. Orthologous to human PSMD8 (proteasome 26S subunit, non-ATPase 8).
SGD Description
Subunit of the 19S regulatory particle of the 26S proteasome lid; synthetically lethal with RPT1, which is an ATPase component of the 19S regulatory particle; physically interacts with Nob1p and Rpn3p; protein abundance increases in response to DNA replication stress
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12387:SF0
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
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Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions