Gene

CYK3

Species
Saccharomyces cerevisiae
Symbol
CYK3
Name
CYtoKinesis
Synonyms
  • YDL117W
Biotype
protein coding gene
Automated Description
Enables enzyme regulator activity. Involved in secondary cell septum biogenesis. Located in cellular bud neck contractile ring. Part of HICS complex. Human ortholog(s) of this gene implicated in myofibrillar myopathy 7. Orthologous to human KY (kyphoscoliosis peptidase).
SGD Description
SH3-domain protein located in the bud neck and cytokinetic actin ring; relocalizes from bud neck to nucleus upon DNA replication stress; activates the chitin synthase activity of Chs2p during cytokinesis; suppressor of growth and cytokinesis defects of chs2 phospho-mutants
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR46333:SF2
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
Viewer Help
249.0k249.5k250.0k250.5k251.0k

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions