Gene

HDA2

Species
Saccharomyces cerevisiae
Symbol
HDA2
Name
Histone DeAcetylase
Synonyms
  • PLO2
  • YDR295C
Biotype
protein coding gene
Automated Description
Enables DNA binding activity and chromatin binding activity. Contributes to histone deacetylase activity. Involved in negative regulation of transcription by RNA polymerase II and regulatory ncRNA-mediated gene silencing. Located in cytosol and nucleus. Part of HDA1 complex.
SGD Description
Subunit of HDA1 histone deacetylase complex; tetrameric trichostatin A-sensitive class II histone deacetylase complex contains Hda1p homodimer and an Hda2p-Hda3p heterodimer; involved in telomere maintenance; Hda2p relocalizes to cytosol in response to hypoxia; other members of the HDA1 histone deacetylase complex, which regulates aging through trehalose metabolism, are Hda1p and Hda3p
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR31882:SF6
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
Viewer Help
1.0528M1.0530M1.0532M1.0534M1.0536M1.0538M1.0540M1.0542M1.0544M1.0546M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions