Gene

RQC1

Species
Saccharomyces cerevisiae
Symbol
RQC1
Name
Ribosome Quality Control
Synonyms
  • YDR333C
Biotype
protein coding gene
Automated Description
Enables protein-macromolecule adaptor activity. Involved in rescue of stalled ribosome and ribosome-associated ubiquitin-dependent protein catabolic process. Located in cytoplasm. Part of RQC complex. Orthologous to human TCF25 (transcription factor 25).
SGD Description
Component of the ribosome quality control complex (RQC); RQC (Rqc1p-Rkr1p-Rqc2p-Cdc48p-Npl4p-Ufd1p) is a ribosome-bound complex required for the degradation of polypeptides arising from stalled translation; required along with Rkr1p for recruitment of the Cdc48p-Npl4p-Ufd1p AAA ATPase complex to the RQC
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR22684:SF0
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
Viewer Help
1.1334M1.1336M1.1338M1.1340M1.1342M1.1344M1.1346M1.1348M1.1350M1.1352M1.1354M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions