Enables NADPH-adrenodoxin reductase activity. Involved in intracellular iron ion homeostasis and ubiquinone biosynthetic process. Located in mitochondrial inner membrane. Used to study Parkinson's disease; auditory system disease; optic atrophy; and retinitis pigmentosa. Orthologous to human FDXR (ferredoxin reductase).
SGD Description
Oxidoreductase of the mitochondrial inner membrane; involved in cytoplasmic and mitochondrial iron homeostasis and required for activity of Fe-S cluster-containing enzymes; one of the few mitochondrial proteins essential for viability