Contributes to SUMO activating enzyme activity. Involved in protein sumoylation. Located in nucleus. Part of SUMO activating enzyme complex. Orthologous to human UBA2 (ubiquitin like modifier activating enzyme 2).
SGD Description
Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Aos1p; activates Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability