Gene

UBA2

Species
Saccharomyces cerevisiae
Symbol
UBA2
Name
UBiquitin Activating
Synonyms
  • UAL1
  • YDR390C
Biotype
protein coding gene
Automated Description
Contributes to SUMO activating enzyme activity. Involved in protein sumoylation. Located in nucleus. Part of SUMO activating enzyme complex. Orthologous to human UBA2 (ubiquitin like modifier activating enzyme 2).
SGD Description
Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Aos1p; activates Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10953:SF5
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
Viewer Help
1.2550M1.2552M1.2554M1.2556M1.2558M1.2560M1.2562M1.2564M1.2566M1.2568M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions