Gene

SAM2

Species
Saccharomyces cerevisiae
Symbol
SAM2
Name
S-AdenosylMethionine requiring
Synonyms
  • ETH2
  • YDR502C
Biotype
protein coding gene
Automated Description
Enables methionine adenosyltransferase activity. Involved in S-adenosylmethionine biosynthetic process and methionine metabolic process. Located in cytoplasmic stress granule. Human ortholog(s) of this gene implicated in hypermethioninemia and lung cancer. Orthologous to several human genes including MAT1A (methionine adenosyltransferase 1A).
SGD Description
S-adenosylmethionine synthetase; catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; comparative analysis suggests that a mitochondrially targeted form may result from translation starting at a non-canonical codon upstream of the annotated start codon
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11964:SF1
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
Viewer Help
1.4534M1.4536M1.4538M1.4540M1.4542M1.4544M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions