Gene

CUP2

Species
Saccharomyces cerevisiae
Symbol
CUP2
Name
Not Available
Synonyms
  • ACE1
  • YGL166W
Biotype
protein coding gene
Automated Description
Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and copper ion binding activity. Involved in positive regulation of transcription by RNA polymerase II and stress response to copper ion. Located in nucleus.
SGD Description
Copper-binding transcription factor; activates transcription of the metallothionein genes CUP1-1 and CUP1-2 in response to elevated copper concentrations; required for regulation of copper genes in response to DNA-damaging reagents; CUP2 has a paralog, HAA1, that arose from the whole genome duplication
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR28088:SF5
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
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191.2k191.3k191.4k191.5k191.6k191.7k191.8k

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions