Gene

ADE57

Species
Saccharomyces cerevisiae
Symbol
ADE57
Name
ADEnine requiring
Synonyms
  • ADE5,7
  • YGL234W
Biotype
protein coding gene
Automated Description
Predicted to enable phosphoribosylamine-glycine ligase activity and phosphoribosylformylglycinamidine cyclo-ligase activity. Predicted to be involved in adenine biosynthetic process and purine nucleotide biosynthetic process. Located in cytoplasm. Orthologous to human GART (phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase).
SGD Description
Bifunctional enzyme of 'de novo' purine nucleotide pathway; contains both phosphoribosylglycinamidine synthetase/glycinamide ribotide synthetase (EC 6.3.4.13) ["Ade5"] and phosphoribosylaminoimidazole synthetase/aminoimidazole ribotide synthetase (EC 6.3.3.1) ["Ade7"] activities
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10520:SF12
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
Viewer Help
56.6k56.8k57.0k57.2k57.4k57.6k57.8k58.0k58.2k58.4k58.6k58.8k

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions