Enables translation initiation factor activity. Involved in translational initiation. Acts upstream of or within negative regulation of translation. Located in cytosolic ribosome. Part of cytosolic small ribosomal subunit. Orthologous to human EIF2A (eukaryotic translation initiation factor 2A).
SGD Description
Eukaryotic initiation factor eIF2A; associates specifically with both 40S subunits and 80S ribosomes, and interacts genetically with both eIF5b and eIF4E; physically interacts with Ssd1p, and associates with mRNAs encoding proteins required for cell wall organization, and some of which require the presence of Ssd1p; translational repressor of cell wall-related proteins; interacts physically and genetically with Xrn1p; homologous to mammalian eIF2A